2001 GMC Sierra 3500 Engine Cooling Parts

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Keep Your 2001 GMC Sierra 3500 in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2001 GMC Sierra 3500 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Thermostats, Thermostat and Water Outlet Gaskets, and Water Pump Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Felpro, Dorman, and Carquest Premium. For example, Felpro Engine Cooling Parts start at just $2.79 with an average 4.6 star rating. Dorman and Carquest Premium offer similar pricing and quality, backed by strong customer feedback. With over 10,194 reviews and a solid 4.0 star average, you can shop with confidence knowing other GMC Sierra 3500 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2001 GMC Sierra 3500 Engine Cooling Part at Advance Auto Parts is around $75.03, with a range that starts at $0.15 and goes up to $778.99. With 123 options in stock from 22 trusted brands, finding the right fit is easy. Popular picks like Driveworks Water Pumps Engine Water Pump, 58-562, Carquest Standard Thermostat: With Seal, 195 Degrees, 13899, and Felpro Engine Water Pump Gasket, 35635 start at just $7.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blower Motor and Related Products and HVAC Electrical Parts. At Advance Auto Parts, we’re here to help you keep your 2001 GMC Sierra 3500 in peak condition, inside and out.

Essential 2001 GMC Sierra 3500 Engine Cooling Parts

Top Street Performance – Top Street Performance Chevrolet LSX 45 Degree Swivel Chrome Aluminum Water Neck, HC8937C (Part No.HC8937C)

Top Street Performance Chevrolet LSX 45 Degree Swivel Chrome Aluminum Water Neck, HC8937C

from

$26.99
Don’t miss a detail with a new water neck from TSP. Composed of high-quality aluminum, they are available for multiple applications in both polished and black finishes. This water neck comes with bolts for easier installation.
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Dorman – Dorman Clutch Fan Blade: Plastic, Cost Effective and Reliable, 621-106 (Part No.621-106)

Dorman Clutch Fan Blade: Plastic, Cost Effective and Reliable, 621-106

from

$139.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
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Dorman – Dorman Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In, 45813 (Part No.45813)

Dorman Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In, 45813

from

$1.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.
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Dorman – Dorman Thermostat Bypass Pipe, 902-901 (Part No.902-901)

Dorman Thermostat Bypass Pipe, 902-901

from

$55.99
This thermostat bypass pipe is designed to match the fit and function of the original pipe on specified applications, and is engineered for reliable performance and durability.
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Imperial – Imperial Thermostatic Fan Control – Preset, 226206 (Part No.226206)

Imperial Thermostatic Fan Control - Preset, 226206

from

$46.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Imperial.
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Felpro – Felpro Engine Coolant Thermostat Housing Gasket, 35762 (Part No.35762)

Felpro Engine Coolant Thermostat Housing Gasket, 35762

from

$4.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
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Felpro – Felpro Engine Coolant Thermostat Gasket, 35632 (Part No.35632)

Felpro Engine Coolant Thermostat Gasket, 35632

from

$4.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
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Autotecnica – Autotecnica Coolant Cap, GM0613020 (Part No.GM0613020)

Autotecnica Coolant Cap, GM0613020

from

$5.29
Autotecnica offers high-quality aftermarket parts for a wide variety of Asian and North American passenger cars and trucks, include braking, cooling, driveline, electrical, engine, fuel, HVAC, steering, and suspension categories. Autotecnica is the smart choice. Whether you’re a DIY enthusiast or professional technician in need of replacement parts that meet OEM specifications, Autotecnica is an excellent alternative to expensive €œGenuine€ components.
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Felpro – Felpro Engine Water Pump Gasket, 35635 (Part No.35635)

Felpro Engine Water Pump Gasket, 35635

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Carquest Premium – Carquest Engine Coolant Thermostat Housing, 85254 (Part No.85254)

Carquest Engine Coolant Thermostat Housing, 85254

from

$54.99
High quality OE replacement part with all components needed to complete the job.
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MAHLE Original – MAHLE Original Engine Coolant Pipe O-Ring, 72224 (Part No.72224)

MAHLE Original Engine Coolant Pipe O-Ring, 72224

from

$1.99
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.
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Dorman – Dorman Engine Cooling Fan Pulley Bracket, 300-825 (Part No.300-825)

Dorman Engine Cooling Fan Pulley Bracket, 300-825

from

$299.99
This engine cooling fan pulley bracket is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.
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Dorman – Dorman Clutch Fan Blade: Plastic, Cost Effective and Reliable, 621-514 (Part No.621-514)

Dorman Clutch Fan Blade: Plastic, Cost Effective and Reliable, 621-514

from

$109.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
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KAI – KAI Radiator Support, GM1225269 (Part No.GM1225269)

KAI Radiator Support, GM1225269

from

$79.99
New Standard Replacement Radiator Support, Upper Deflector
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Dorman – Dorman Water Pump Outlet Pipe, 626-661 (Part No.626-661)

Dorman Water Pump Outlet Pipe, 626-661

from

$91.99
This engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles. It is engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion.
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Carquest Premium – Carquest Cooling System Tester Adapter, 12032 (Part No.12032)

Carquest Cooling System Tester Adapter, 12032

from

$95.99
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive cooling systems.
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Carquest Premium – Carquest Coolant Temperature Switch, WTC1035 (Part No.WTC1035)

Carquest Coolant Temperature Switch, WTC1035

from

$29.99
Carquest Premium coolant temperature sensors and switches are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry, Carquest Premium coolant temperature sensors and switches undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium coolant temperature sensors and switches are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
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US MOTOR WORKS – US MOTOR WORKS Water Pump with Fan Clutch, MCK1069 (Part No.MCK1069)

US MOTOR WORKS Water Pump with Fan Clutch, MCK1069

from

$177.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.
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Dorman – Dorman Thermostat Assembly: Includes Housing, 902-2836 (Part No.902-2836)

Dorman Thermostat Assembly: Includes Housing, 902-2836

from

$78.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 185 Degrees, 14728 (Part No.14728)

Carquest Standard Thermostat: With Seal, 185 Degrees, 14728

from

$43.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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GM Genuine Parts – GM Genuine Parts Engine Coolant Thermostat Water Inlet Assembly, 15-10412 (Part No.15-10412)

GM Genuine Parts Engine Coolant Thermostat Water Inlet Assembly, 15-10412

from

$72.99
GM Genuine Parts Engine Coolant Thermostat / Water Inlet Assemblies are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These engine coolant thermostat / water inlet assemblies contain the engine thermostat and water inlet housing. The engine coolant thermostat controls the flow of coolant through the radiator; enabling the engine to reach and maintain its normal operating temperature. The water inlet housing connects the radiator hoses to the thermostat. For certain applications, the water inlet contains threaded holes or ports for sensors and switches. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Carquest Premium – Carquest Radiator: With Engine and Transmission Oil Coolers, 432306 (Part No.432306)

Carquest Radiator: With Engine and Transmission Oil Coolers, 432306

from

$281.99
Reach Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Reach Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.
See More

Dorman – Dorman Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 186 Degrees, 902-700 (Part No.902-700)

Dorman Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 186 Degrees, 902-700

from

$33.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
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Dorman – Help – Dorman – Help Radiator Drain Cocks, 61136 (Part No.61136)

Dorman - Help Radiator Drain Cocks, 61136

from

$5.99
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.
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Stant – Stant Thermostat Gasket (Sold by each), 30989 (Part No.30989)

Stant Thermostat Gasket (Sold by each), 30989

from

$1.99
Stant Thermostat Gasket (Sold by each), 30989.
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Felpro – Felpro Engine Water Pump Gasket, 35756 (Part No.35756)

Felpro Engine Water Pump Gasket, 35756

from

$3.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
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Felpro – Felpro Engine Water Pump Installation Kit, ES 71347 (Part No.ES 71347)

Felpro Engine Water Pump Installation Kit, ES 71347

from

$33.99
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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KAI – KAI Cooling Fan Shroud, GM3110134 (Part No.GM3110134)

KAI Cooling Fan Shroud, GM3110134

from

$25.99
New Platinum Pro Upper Fan Shroud, Without Rear A/C
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Most Popular Thermostats for 2001 GMC Sierra 3500s

Enhance your 2001 GMC Sierra 3500 with one of the 17 Thermostats we have in stock, starting at just $7.99.

Motorad – Motorad Standard Thermostat: With Seal, 180 Degrees, 185 Degrees, 447448 (Part No.447448)

Motorad Standard Thermostat: With Seal, 180 Degrees, 185 Degrees, 447448

from

$49.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 187 Degrees, 14948 (Part No.14948)

Carquest Standard Thermostat: With Seal, 187 Degrees, 14948

from

$18.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 195 Degrees, 13899 (Part No.13899)

Carquest Standard Thermostat: With Seal, 195 Degrees, 13899

from

$7.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Integrated Thermostat Housing: With Seal, 187 Degrees, 14298 (Part No.14298)

Carquest Integrated Thermostat Housing: With Seal, 187 Degrees, 14298

from

$22.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 185 Degrees, 14728 (Part No.14728)

Carquest Standard Thermostat: With Seal, 185 Degrees, 14728

from

$43.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 180 Degrees, 14738 (Part No.14738)

Carquest Standard Thermostat: With Seal, 180 Degrees, 14738

from

$42.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Motorad UltraStats – Motorad UltraStats Thermostat: With Seal, 187 Degrees, 5456-187 (Part No.5456-187)

Motorad UltraStats Thermostat: With Seal, 187 Degrees, 5456-187

from

$28.99
UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resitance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components.
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Motorad UltraStats – Motorad UltraStats UltraStat Thermostat: With Seal, 195 Degrees, 5267-195 (Part No.5267-195)

Motorad UltraStats UltraStat Thermostat: With Seal, 195 Degrees, 5267-195

from

$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.
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Mr. Gasket – Mr. Gasket Thermostat – 180 Degree, 6368 (Part No.6368)

Mr. Gasket Thermostat - 180 Degree, 6368

from

$39.19
Designed to open at 180 degrees every time, regardless of engine rpm, and it’s high-flow design and brass and copper construction eliminate the damaging effects of cycling when you’re stuck in stop-and-go traffic. It includes the rubber gasket and has a pressure relief valve.
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Mr. Gasket – Mr. Gasket Thermostat – 160 Degree, 6367 (Part No.6367)

Mr. Gasket Thermostat - 160 Degree, 6367

from

$39.19
Designed to open at 160 degrees every time, regardless of engine rpm, and it’s high-flow design and brass and copper construction eliminate the damaging effects of cycling when you’re stuck in stop-and-go traffic. It includes the rubber gasket and has a pressure relief valve.
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Motorad – Motorad Standard Thermostat: With Seal, 187 Degrees, 524-190 (Part No.524-190)

Motorad Standard Thermostat: With Seal, 187 Degrees, 524-190

from

$17.49
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 180 Degrees, 456-180 (Part No.456-180)

Carquest Standard Thermostat: With Seal, 180 Degrees, 456-180

from

$48.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
See More

Carquest Premium – Carquest Integrated Thermostat Housing: With Seal, 180 Degrees, 379-180 (Part No.379-180)

Carquest Integrated Thermostat Housing: With Seal, 180 Degrees, 379-180

from

$36.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Integrated Thermostat Housing: With Seal, 160 Degrees, 379-160 (Part No.379-160)

Carquest Integrated Thermostat Housing: With Seal, 160 Degrees, 379-160

from

$17.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 160 Degrees, 267-160 (Part No.267-160)

Carquest Standard Thermostat: With Seal, 160 Degrees, 267-160

from

$14.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Engine Coolant HD Thermostat: With Seal, 180 Degrees, 267-180 (Part No.267-180)

Carquest Engine Coolant HD Thermostat: With Seal, 180 Degrees, 267-180

from

$13.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable
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Carquest Premium – Carquest Standard Thermostat: With Seal, 160 Degrees, 456-160 (Part No.456-160)

Carquest Standard Thermostat: With Seal, 160 Degrees, 456-160

from

$7.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Best-Selling 2001 GMC Sierra 3500 Thermostat and Water Outlet Gaskets

Upgrade your Sierra 3500 with one of our 2 best-selling Thermostat and Water Outlet Gaskets, earning an average 5 stars rating across 1 reviews.

Felpro – Felpro Multi-Purpose O-Ring, 35759 (Part No.35759)

Felpro Multi-Purpose O-Ring, 35759

from

$2.79
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
See More

Victor Reinz – Victor Reinz Engine Coolant Thermostat Gasket, 71-14044-00 (Part No.71-14044-00)

Victor Reinz Engine Coolant Thermostat Gasket, 71-14044-00

from

$2.69
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.
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Top-Quality Water Pump Gaskets for 2001 GMC Sierra 3500s

Choose a high-quality OEM or aftermarket Water Pump Gasket for GMC Sierra 3500s and enjoy top-notch performance from $3.29.

Felpro – Felpro Engine Water Pump Gasket, 35664 (Part No.35664)

Felpro Engine Water Pump Gasket, 35664

from

$7.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
See More

Felpro – Felpro Engine Water Pump Gasket, 35635 (Part No.35635)

Felpro Engine Water Pump Gasket, 35635

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
See More

Felpro – Felpro Engine Water Pump Gasket, 35758 (Part No.35758)

Felpro Engine Water Pump Gasket, 35758

from

$7.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
See More

Victor Reinz – Victor Reinz Engine Water Pump Gasket, 71-14023-00 (Part No.71-14023-00)

Victor Reinz Engine Water Pump Gasket, 71-14023-00

from

$3.29
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.
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Top Picks for 2001 GMC Sierra 3500 Radiators

Invest in one of our 8 durable Radiators for your 2001 GMC, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – Carquest Radiator: With Engine and Transmission Oil Coolers, 432306 (Part No.432306)

Carquest Radiator: With Engine and Transmission Oil Coolers, 432306

from

$281.99
Reach Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Reach Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.
See More

Carquest Premium – Carquest Radiator: With Transmission Oil Cooler, 432295 (Part No.432295)

Carquest Radiator: With Transmission Oil Cooler, 432295

from

$290.99
Reach Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Reach Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.
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Carquest Premium – Carquest Radiator, 432350 (Part No.432350)

Carquest Radiator, 432350

from

$494.99
A global leader in the manufacture and distribution of aftermarket cooling products for automotive, heavy truck, and industrial applications. Specialized in the production of OE-quality Radiators, Condensers, and Charge Air Coolers for US and international markets, covering over 10,000 part numbers worldwide. Reach Cooling is headquartered in Miami, Florida, with additional distribution centers in Los Angeles, California and a manufacturing plant in Shanghai, China.
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Carquest Premium – Carquest Radiator, 432333 (Part No.432333)

Carquest Radiator, 432333

from

$778.99
Reach Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Reach Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.
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Carquest Premium – Carquest Radiator, 432334 (Part No.432334)

Carquest Radiator, 432334

from

$453.99
A global leader in the manufacture and distribution of aftermarket cooling products for automotive, heavy truck, and industrial applications. Specialized in the production of OE-quality Radiators, Condensers, and Charge Air Coolers for US and international markets, covering over 10,000 part numbers worldwide. Reach Cooling is headquartered in Miami, Florida, with additional distribution centers in Los Angeles, California and a manufacturing plant in Shanghai, China.
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KAI – KAI Radiator, RAD2537 (Part No.RAD2537)

KAI Radiator, RAD2537

from

$445.99
New Platinum Pro Radiator, 8.1 Liter Gas Engine, Automatic Transmission, With Engine Oil Cooler, With Transmission Oil Cooler
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Proform – Proform Premium Radiator with Transmission and Engine Oil Coolers, 22840116 (Part No.22840116)

Proform Premium Radiator with Transmission and Engine Oil Coolers, 22840116

from

$304.99
PROFORM Radiators are Engineered to Perform. Built to Last. Discover the unmatched quality of PROFORM, featuring our high-performance Radiator designed to keep your engine running cool under pressure. Built with precision engineering and premium materials, this radiator delivers dependable cooling performance whether you are restoring, upgrading, or maintaining your vehicle. PROFORM is your trusted source for performance-driven components that combine reliability, durability, and superior fitment. The PROFORM Radiator is a critical component in maintaining engine temperature, protecting performance, and extending engine life. Whether you are replacing a worn unit or upgrading your cooling system, this radiator is built to meet demanding standards and real-world driving conditions. At PROFORM, we understand that downtime is not an option. Upgrade with confidence. Choose PROFORM and experience performance without compromise.
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Proform – Proform Premium Radiator with Transmission Oil Cooler, 22840117 (Part No.22840117)

Proform Premium Radiator with Transmission Oil Cooler, 22840117

from

$304.99
PROFORM Radiators are Engineered to Perform. Built to Last. Discover the unmatched quality of PROFORM, featuring our high-performance Radiator designed to keep your engine running cool under pressure. Built with precision engineering and premium materials, this radiator delivers dependable cooling performance whether you are restoring, upgrading, or maintaining your vehicle. PROFORM is your trusted source for performance-driven components that combine reliability, durability, and superior fitment. The PROFORM Radiator is a critical component in maintaining engine temperature, protecting performance, and extending engine life. Whether you are replacing a worn unit or upgrading your cooling system, this radiator is built to meet demanding standards and real-world driving conditions. At PROFORM, we understand that downtime is not an option. Upgrade with confidence. Choose PROFORM and experience performance without compromise.
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Top-Rated Water Pumps for 2001 GMC Sierra 3500s

Make a smart move for your 2001 GMC Sierra 3500 with products all priced from $103.99 to $298.99.

Carquest Premium – Carquest Engine Water Pump: New, Gasket/Seals Included, T7052 (Part No.T7052)

Carquest Engine Water Pump: New, Gasket/Seals Included, T7052

from

$150.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.
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Driveworks Water Pumps – Driveworks Water Pumps Engine Water Pump, 58-562 (Part No.58-562)

Driveworks Water Pumps Engine Water Pump, 58-562

from

$103.99
This replacement engine water pump is leak and flow tested. Gaskets and seals are included where applicable.
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Carquest Premium – Carquest Engine Water Pump: New, Gasket/Seals Included, T5097 (Part No.T5097)

Carquest Engine Water Pump: New, Gasket/Seals Included, T5097

from

$133.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
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Carquest Premium – Carquest Engine Water Pump: New, Gasket/Seals Included, T2249 (Part No.T2249)

Carquest Engine Water Pump: New, Gasket/Seals Included, T2249

from

$104.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
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ACDelco – ACDelco Water Pump Kit, 252-845 (Part No.252-845)

ACDelco Water Pump Kit, 252-845

from

$211.99
An ACDelco Professional, premium aftermarket Engine Water Pump circulates coolant through your vehicle’s radiator and engine system to help maintain proper engine temperature and performance. The gaskets, seals, and O-rings packaged with this Professional, premium aftermarket water pump help guarantee that all necessary parts are available for trouble-free installation. ACDelco Professional Water Pumps are a high quality replacement for many vehicles on the road today. This premium aftermarket replacement engine water pump is manufactured to meet your expectations for fit, form, and function.
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AISIN – AISIN Engine Water Pump Assembly, WPGM-708V (Part No.WPGM-708V)

AISIN Engine Water Pump Assembly, WPGM-708V

from

$298.99
OE Engineered and Manufactured Water Pumps
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Carquest Premium – Carquest Engine Water Pump with Thermostat and Housing, T7181 (Part No.T7181)

Carquest Engine Water Pump with Thermostat and Housing, T7181

from

$188.99
Manufactured to meet or exceed OEM specifications.
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Carquest Premium – Carquest Water Pump Kit, T7052-RF (Part No.T7052-RF)

Carquest Water Pump Kit, T7052-RF

from

$179.99
Carquest Premium Water Pump Kits are engineered to save time, featuring installed gaskets and zinc-coated Axi-Rad bolts that are pre-mounted for faster, easier installation. Every pump is factory tested to ensure superior quality, meeting or exceeding original equipment standards. With application-specific designs, Carquest Premium Water Pump Kits provide an accurate fit and reliable performance, delivering quality you can count on.
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Top-Rated Engine Cooling Part Brands For Your 2001 GMC Sierra 3500

When it comes to finding the perfect Engine Cooling Part for your 2001 GMC Sierra 3500, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 22 trusted brands. We carry the most popular Engine Cooling Part brands including Felpro, Carquest Premium, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $2.79. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2001 GMC Sierra 3500, providing peace of mind with parts that meet or exceed OEM standards.

Popular Felpro 2001 GMC Sierra 3500 Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2001 GMC Sierra 3500, Advance Auto Parts has exactly what you need with our selection of Felpro Engine Cooling Parts. We have 3 Felpro Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $2.79 and an average cost of $15.26, you’ll find the perfect Engine Cooling Part for your needs and budget. Felpro Engine Cooling Parts for the 2001 GMC Sierra 3500 come highly rated, with over 15 customer reviews and an impressive average rating of 4.6 stars. Choosing a Felpro Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Felpro Engine Water Pump Installation Kit, ES 71347
from $33.99
(5)
Felpro Engine Water Pump Installation Kit, ES 71347
“Was what I needed”
Felpro Engine Water Pump Gasket Kit, ES 73010
from $8.99
(9)
Felpro Engine Water Pump Gasket Kit, ES 73010
“OEM Quality, no rtv needed to make these work which makes it so much faster if you need to replace the water pump again in the future.”
Felpro Multi-Purpose O-Ring, 35759
from $2.79
(1)
Felpro Multi-Purpose O-Ring, 35759
“This is the big o-ring that connects the top, rear side of the thermostat housing with the metal portion of the upper radiator pipe. This is not the s”

Top-Quality Carquest Premium 2001 GMC Sierra 3500 Engine Cooling Parts

For those in search of a high-quality Engine Cooling Part for their 2001 GMC Sierra 3500, Advance Auto Parts offers a great selection of Carquest Premium Engine Cooling Parts. With 3 Carquest Premium Engine Cooling Parts in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Engine Cooling Parts start at just $7.99, with an average price of $59.32, giving you a range of options to suit your budget. Backed by over 665 customer ratings and an average rating of 4.5 stars, Carquest Premium Engine Cooling Parts provide both reliability and excellent performance. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Carquest Engine Water Pump: New, Gasket/Seals Included, T7052
from $150.99
(371)
Carquest Engine Water Pump: New, Gasket/Seals Included, T7052
“Direct fit and no problems”
Carquest Standard Thermostat: With Seal, 187 Degrees, 14948
from $18.99
(189)
Carquest Standard Thermostat: With Seal, 187 Degrees, 14948
“had to return, base too large to fit into my new water pump”

FAQs for 2001 GMC Sierra 3500 Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2001 GMC Sierra 3500s?

Out of 123 Engine Cooling Parts that fit 2001 GMC Sierra 3500s, the following parts are the top sellers:

What’s the price range for 2001 GMC Sierra 3500 Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2001 GMC Sierra 3500 range from $0.15 up to $778.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2001 GMC Sierra 3500?

The average price for Engine Cooling Parts for the 2001 GMC Sierra 3500 is $75.03. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other GMC Sierra 3500 model years?

Yes, we carry Engine Cooling Parts for 5 model years of GMC Sierra 3500s between 2002 and 2007. The following model years are the most popular for Engine Cooling Part purchases: 2007, 2006, 2005, 2004, 2003, and 2002.

What are the cheapest Engine Cooling Parts for my 2001 GMC Sierra 3500?

Does Advance Auto Parts sell Engine Cooling Parts for any other 2001 GMC models?

What types of Engine Cooling Parts do you sell for my 2001 GMC Sierra 3500?

As of 8/2/26, these are some of the most in-demand types of Engine Cooling Parts for a 2001 GMC Sierra 3500:

Can I get help with 2001 GMC Sierra 3500 Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Engine Cooling Parts and more.

What is your return policy for GMC Sierra 3500 Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new GMC Sierra 3500 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.