2001 GMC C6500 Topkick Wheel Seals

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Keep Your 2001 GMC C6500 Topkick in Top Shape with a Quality Wheel Seal

When it comes to maintaining or upgrading your 2001 GMC C6500 Topkick, choosing high-quality parts is crucial for ensuring your vehicle stays in top shape, whether you’re tackling a repair or enhancing performance. At Advance Auto Parts, we know how important it is to find the right Wheel Seal for your C6500 Topkick. We currently carry a top Wheel Seal in stock that is built to last. Whether you’re replacing a damaged Wheel Seal or looking to upgrade, our selection for the 2001 GMC C6500 Topkick ensures you’ll find exactly what you need to keep your vehicle looking and performing its best.

Explore Related Parts

And while you’re here, don’t forget to check out related part categories like Hubcaps and Wheel Bearings to complete your upgrade or repair project. At Advance Auto Parts, we’re proud to offer the parts and expertise to keep your 2001 GMC C6500 Topkick running smoothly and looking great.

Essential 2001 GMC C6500 Topkick Wheel Seals

National – Wheel Seal (Part No.380023A)

Wheel Seal

from

$59.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Gold 38 Series seals feature advanced technology
  • Temperature range: -100 Deg. F to 450 Deg. F; -73 Deg. C to 232 Deg. C
  • Triple barrier contamination system for ultimate in dirt exclusion
  • Proprietary PTFE compound endures extreme temperatures, compatible with mixed lubricants and has lowest friction
  • Patented, lay-down bi-directional sealing lip provides greater sealing surface especially during wheel end movement
See More

Driveworks – Oil Seal (Part No.S-370023A)

Oil Seal

from

$31.49
Product Features:
  • Brand may vary by location
See More

National – Wheel Seal (Part No.370003A)

Wheel Seal

from

$49.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Dynamic Edge Red 37 Series oil bath seals deliver dependable point contact seal
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Unitized construction provides greater structural integrity, easier installation and main lip protection
  • Abrasion-resistant nitrile with spring-loaded main lip for positive sealing with reduced shaft interference
  • Unique rubber I.D. and O.D. includes patented SURE-LOCK ribs that prevent shaft leaks and bore contamination
  • Temperature Range: -40 Deg. F to 225 Deg. F; -40 Deg. C to 107 Deg. C
See More

National – Wheel Seal (Part No.370008A)

Wheel Seal

from

$43.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Red 37 Series oil bath seals deliver dependable point contact seal
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Unitized construction provides greater structural integrity, easier installation and main lip protection
  • Abrasion-resistant nitrile with spring-loaded main lip for positive sealing with reduced shaft interference
  • Unique rubber I.D. and O.D. includes patented SURE-LOCK ribs that prevent shaft leaks and bore contamination
See More

National – Wheel Seal (Part No.375023A)

Wheel Seal

from

$48.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Dynamic Edge Hand Installable Red 375 Series oil bath seals deliver dependable point contact seal and easy installation
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Unitized construction provides greater structural integrity, easier installation and main lip protection
  • Abrasion-resistant nitrile with spring-loaded main lip for positive sealing with reduced shaft interference
  • Unique rubber I.D. and O.D. includes patented SURE-LOCK ribs that prevent shaft leaks and bore contamination
See More

National – Wheel Seal (Part No.370023A)

Wheel Seal

from

$45.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Dynamic Edge Red 37 Series oil bath seals deliver dependable point contact seal
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Unitized construction provides greater structural integrity, easier installation and main lip protection
  • Abrasion-resistant nitrile with spring-loaded main lip for positive sealing with reduced shaft interference
  • Unique rubber I.D. and O.D. includes patented SURE-LOCK ribs that prevent shaft leaks and bore contamination
  • Temperature Range: -40 Deg. F to 225 Deg. F; -40 Deg. C to 107 Deg. C
See More

Schaeffler – Shaft Seal (Part No.SS3349)

Shaft Seal

from

$45.49
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

National – Wheel Seal (Part No.380003A)

Wheel Seal

from

$55.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Gold 38 Series seals feature advanced technology
  • Temperature range: -100 Deg. F to 450 Deg. F; -73 Deg. C to 232 Deg. C
  • Triple barrier contamination system for ultimate in dirt exclusion
  • Proprietary PTFE compound endures extreme temperatures, compatible with mixed lubricants and has lowest friction
  • Patented, lay-down bi-directional sealing lip provides greater sealing surface especially during wheel end movement
See More

Most Popular Rear Wheel Seal for 2001 GMC C6500 Topkicks

Enhance your 2001 GMC C6500 Topkick with this popular Rear Wheel Seal we have in stock, for $45.49.

Schaeffler – Shaft Seal (Part No.SS3349)

Shaft Seal

from

$45.49
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

FAQs for 2001 GMC C6500 Topkick Wheel Seals

What’s the price range for 2001 GMC C6500 Topkick Wheel Seals?

We currently have just one Wheel Seals for the 2001 GMC C6500 Topkick in stock: Shaft Seal and it costs $45.49.

Does Advance Auto Parts sell Wheel Seals for other GMC C6500 Topkick model years?

Yes, we carry Wheel Seals for 10 model years of GMC C6500 Topkicks between 1997 and 2009. The following model years are the most popular for Wheel Seal purchases: 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2000, and 1999.

Does Advance Auto Parts sell Wheel Seals for any other 2001 GMC models?

Yes. We stock Wheel Seals for 17 other popular 2001 GMC models. Some of the most popular are 2001 Yukon Wheel Seals, 2001 Sierra 1500 Wheel Seals, 2001 Yukon XL 1500 Wheel Seals, 2001 Sierra 2500 HD Wheel Seals, and 2001 Yukon XL 2500 Wheel Seals.

What types of Wheel Seals do you sell for my 2001 GMC C6500 Topkick?

We currently have just 1 Wheel Seal in stock for a 2001 GMC C6500 Topkick, and as of 3/1/26, it is a Rear Wheel Seal.

Can I get help with 2001 GMC C6500 Topkick Wheel Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Wheel Seals and more.

What is your return policy for GMC C6500 Topkick Wheel Seals?

Advance Auto Parts keeps returns simple. For new GMC C6500 Topkick Wheel Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.