2000 Peterbilt 378 Engine Cooling Parts

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Keep Your 2000 Peterbilt 378 in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2000 Peterbilt 378 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Water Pumps, Thermostat and Water Outlet Assemblies, and Thermostats. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium. For example, Carquest Premium Engine Cooling Parts start at just $86.99 with an average 4.5 star rating. With over 30 reviews and a solid 4.7 star average, you can shop with confidence knowing other Peterbilt 378 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2000 Peterbilt 378 Engine Cooling Part at Advance Auto Parts is around $128.61, with a range that starts at $4.99 and goes up to $1,209.99. With 31 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Carquest Thermostat: With Seal, 190 Degrees, 14539, Carquest Coolant Spin-On Filter with Bte Formula, 89071, and Carquest Coolant Spin-On Filter with Bta Plus Formula, 96324 start at just $29.49 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blend Doors and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2000 Peterbilt 378 in peak condition, inside and out.

Essential 2000 Peterbilt 378 Engine Cooling Parts

Carquest Premium – Carquest Coolant Temperature Sensor, WTA2369 (Part No.WTA2369)

Carquest Coolant Temperature Sensor, WTA2369

from

$4.99
Approved materials for increased durability in even the most extreme temperatures. All Carquest Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
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Carquest Premium – Carquest Coolant Temperature Sensor 1TS1035, WTC1082 (Part No.WTC1082)

Carquest Coolant Temperature Sensor 1TS1035, WTC1082

from

$55.99
Carquest Premium coolant temperature sensors and switches are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry, Carquest Premium coolant temperature sensors and switches undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium coolant temperature sensors and switches are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
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Carquest Premium – Carquest Coolant Temperature Sensor, WTA2365 (Part No.WTA2365)

Carquest Coolant Temperature Sensor, WTA2365

from

$4.99
Approved materials for increased durability in even the most extreme temperatures. All Carquest Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
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Carquest Premium – Carquest Coolant Spin-On Filter with Bte Formula, 89071 (Part No.89071)

Carquest Coolant Spin-On Filter with Bte Formula, 89071

from

$29.49
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Coolant Spin-On Filter with Bta Plus Formula, 99065 (Part No.99065)

Carquest Coolant Spin-On Filter with Bta Plus Formula, 99065

from

$71.99
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Coolant Spin-On Filter with Bta Plus Formula, 96324 (Part No.96324)

Carquest Coolant Spin-On Filter with Bta Plus Formula, 96324

from

$29.99
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Coolant Spin-On Filter with Bta Plus Formula, 89197 (Part No.89197)

Carquest Coolant Spin-On Filter with Bta Plus Formula, 89197

from

$60.99
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Coolant Spin-On Filter with Bta Plus Formula, 89075 (Part No.89075)

Carquest Coolant Spin-On Filter with Bta Plus Formula, 89075

from

$59.99
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Coolant Spin-On Filter with Bta Plus Formula, 89112 (Part No.89112)

Carquest Coolant Spin-On Filter with Bta Plus Formula, 89112

from

$134.99
Carquest Premium Coolant Filters protect your engine’s cooling system by filtering out rust, scale, dirt, and other particles from the coolant fluid. Coolant filters remove contaminants that build up and cause clogging or corrosion in the radiator, water pump, heater core, and engine passages. By keeping the coolant clean and effective, these filters help prevent overheating and ensure optimal engine performance. Carquest Premium Coolant Filters are designed to meet or exceed the performance requirements of the Original Equipment Manufacturer (OEM).
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Carquest Premium – Carquest Water Pump Kit, T2267-RF (Part No.T2267-RF)

Carquest Water Pump Kit, T2267-RF

from

$70.99
Carquest Premium Water Pump Kits are engineered to save time, featuring installed gaskets and zinc-coated Axi-Rad bolts that are pre-mounted for faster, easier installation. Every pump is factory tested to ensure superior quality, meeting or exceeding original equipment standards. With application-specific designs, Carquest Premium Water Pump Kits provide an accurate fit and reliable performance, delivering quality you can count on.
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Gates – Gates FleetRunner Heavy-Duty Micro-V Serpentine Drive Belt, K120924HD (Part No.K120924HD)

Gates FleetRunner Heavy-Duty Micro-V Serpentine Drive Belt, K120924HD

from

$180.99
Gates Fleet Runner Micro-V Belts are designed for the toughest applications. Fleet Runner construction provides superior flexibility, stability, load capacity, and unsurpassed belt life. Patented materials deliver peak performance at extreme prolonged operating temperatures, making this belt the ultimate problem solver. An advanced blend of EPDM rubber technology withstands the modern threats of deterioration from increased exposure to ozone and water-based coolants. Fleet Runner does this all while providing the lowest cost per mile for fleets, including 3/4 and 1 ton pickups.
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Gates – Gates Heavy-Duty Engine Water Pump, 41173HD (Part No.41173HD)

Gates Heavy-Duty Engine Water Pump, 41173HD

from

$155.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Carquest Premium – Carquest Thermostat: With Seal, 170 Degrees, 14537 (Part No.14537)

Carquest Thermostat: With Seal, 170 Degrees, 14537

from

$52.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 180 Degrees, 14288 (Part No.14288)

Carquest Standard Thermostat: With Seal, 180 Degrees, 14288

from

$37.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Thermostat: With Seal, 180 Degrees, 14538 (Part No.14538)

Carquest Thermostat: With Seal, 180 Degrees, 14538

from

$38.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Heavy Duty Thermostat: 180 Degrees, 14978 (Part No.14978)

Carquest Heavy Duty Thermostat: 180 Degrees, 14978

from

$20.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Dorman – HD Solutions – Dorman – HD Solutions Low Coolant Level Sensor, 904-7363 (Part No.904-7363)

Dorman - HD Solutions Low Coolant Level Sensor, 904-7363

from

$273.99
This engine coolant level sensor is designed to match the fit and function of the original sensor on specified vehicles, and is engineered for durability and reliable performance.
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Carquest Premium – Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15218 (Part No.15218)

Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15218

from

$24.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15198 (Part No.15198)

Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15198

from

$55.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Heavy Duty Thermostat: 175 Degrees, 14857 (Part No.14857)

Carquest Heavy Duty Thermostat: 175 Degrees, 14857

from

$64.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Engine Coolant HD Thermostat: With Seal, 190 Degrees, 15199 (Part No.15199)

Carquest Engine Coolant HD Thermostat: With Seal, 190 Degrees, 15199

from

$68.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Standard Thermostat: With Seal, 190 Degrees, 14289 (Part No.14289)

Carquest Standard Thermostat: With Seal, 190 Degrees, 14289

from

$36.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Engine Coolant HD Thermostat, 15006 (Part No.15006)

Carquest Engine Coolant HD Thermostat, 15006

from

$86.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Most Popular Water Pumps for 2000 Peterbilt 378s

Enhance your 2000 Peterbilt 378 with one of the 6 Water Pumps we have in stock, starting at just $449.99.

Gates – Gates Heavy-Duty Engine Water Pump, 44066HD (Part No.44066HD)

Gates Heavy-Duty Engine Water Pump, 44066HD

from

$449.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Gates – Gates Heavy-Duty Engine Water Pump, 44062HD (Part No.44062HD)

Gates Heavy-Duty Engine Water Pump, 44062HD

from

$1209.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Gates – Gates Heavy-Duty Engine Water Pump, 44051HD (Part No.44051HD)

Gates Heavy-Duty Engine Water Pump, 44051HD

from

$783.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Gates – Gates Heavy-Duty Engine Water Pump, 46002HD (Part No.46002HD)

Gates Heavy-Duty Engine Water Pump, 46002HD

from

$694.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Gates – Gates Heavy-Duty Engine Water Pump, 44060HD (Part No.44060HD)

Gates Heavy-Duty Engine Water Pump, 44060HD

from

$646.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Gates – Gates Heavy-Duty Engine Water Pump, 44052HD (Part No.44052HD)

Gates Heavy-Duty Engine Water Pump, 44052HD

from

$588.99
Gates carries a huge line of water pumps for heavy duty applications. Our heavy duty water pump offering is designed to handle rugged Fleet standards.
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Best-Selling 2000 Peterbilt 378 Thermostat and Water Outlet Assembly

Upgrade your 378 with our best-selling Thermostat and Water Outlet Assembly with a 4 Starts rating across 1 review.

Carquest Premium – Carquest Engine Coolant HD Thermostat, 15006 (Part No.15006)

Carquest Engine Coolant HD Thermostat, 15006

from

$86.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Top-Quality Thermostats for 2000 Peterbilt 378s

Choose a high-quality OEM or aftermarket Thermostat for Peterbilt 378s and enjoy top-notch performance from $20.99.

Carquest Premium – Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15008 (Part No.15008)

Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15008

from

$96.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Engine Coolant HD Thermostat, 15009 (Part No.15009)

Carquest Engine Coolant HD Thermostat, 15009

from

$87.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Thermostat: With Seal, 190 Degrees, 14539 (Part No.14539)

Carquest Thermostat: With Seal, 190 Degrees, 14539

from

$39.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Heavy Duty Thermostat: With Seal, 190 Degrees, 15229 (Part No.15229)

Carquest Heavy Duty Thermostat: With Seal, 190 Degrees, 15229

from

$51.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15228 (Part No.15228)

Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15228

from

$50.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Thermostat: With Seal, 190 Degrees, 14239 (Part No.14239)

Carquest Thermostat: With Seal, 190 Degrees, 14239

from

$41.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Carquest Premium – Carquest Engine Coolant HD Thermostat: With Seal, 190 Degrees, 15199 (Part No.15199)

Carquest Engine Coolant HD Thermostat: With Seal, 190 Degrees, 15199

from

$68.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Motorad – Motorad Heavy Duty Engine Coolant Thermostat: 180 Degrees, 4060-80 (Part No.4060-80)

Motorad Heavy Duty Engine Coolant Thermostat: 180 Degrees, 4060-80

from

$54.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.
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Motorad – Motorad Heavy Duty Engine Coolant Thermostat: 190 Degrees, 4060-90 (Part No.4060-90)

Motorad Heavy Duty Engine Coolant Thermostat: 190 Degrees, 4060-90

from

$47.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.
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Motorad – Motorad Heavy Duty Thermostat: 160 Degrees, 4060-60 (Part No.4060-60)

Motorad Heavy Duty Thermostat: 160 Degrees, 4060-60

from

$32.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.
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Motorad – Motorad Heavy Duty Engine Coolant Thermostat: 235 Degrees, 4079-35 (Part No.4079-35)

Motorad Heavy Duty Engine Coolant Thermostat: 235 Degrees, 4079-35

from

$31.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Motorad – Motorad Integrated Housing HD Thermostat: 225 Degrees, 4078-25 (Part No.4078-25)

Motorad Integrated Housing HD Thermostat: 225 Degrees, 4078-25

from

$20.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Top Picks for 2000 Peterbilt 378 Thermostat – Optional Replacements

Invest in one of our 3 durable Thermostat – Optional Replacements for your 2000 Peterbilt, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – Carquest Thermostat: With Seal, 160 Degrees, 14536 (Part No.14536)

Carquest Thermostat: With Seal, 160 Degrees, 14536

from

$36.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
See More

Carquest Premium – Carquest Thermostat: With Seal, 170 Degrees, 14537 (Part No.14537)

Carquest Thermostat: With Seal, 170 Degrees, 14537

from

$52.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
See More

Carquest Premium – Carquest Thermostat: With Seal, 180 Degrees, 14538 (Part No.14538)

Carquest Thermostat: With Seal, 180 Degrees, 14538

from

$38.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Coolant Temperature Sensors for 2000 Peterbilt 378s

Make a smart move for your 2000 Peterbilt 378 with products all priced from $4.99.

Carquest Premium – Carquest Coolant Temperature Sensor, WTA2372 (Part No.WTA2372)

Carquest Coolant Temperature Sensor, WTA2372

from

$4.99
Approved materials for increased durability in even the most extreme temperatures. All Carquest Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
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Carquest Premium – Carquest Coolant Temperature Sensor, WTA2369 (Part No.WTA2369)

Carquest Coolant Temperature Sensor, WTA2369

from

$4.99
Approved materials for increased durability in even the most extreme temperatures. All Carquest Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
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Top-Rated Engine Cooling Part Brands For Your 2000 Peterbilt 378

When it comes to finding the perfect Engine Cooling Part for your 2000 Peterbilt 378, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 4 trusted brands. We carry the most popular Engine Cooling Part brands including Carquest Premium, and more, all known for their exceptional customer ratings (average brand rating of 4.5 stars) and competitive prices, as low as $86.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2000 Peterbilt 378, providing peace of mind with parts that meet or exceed OEM standards.

Popular Carquest Premium 2000 Peterbilt 378 Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2000 Peterbilt 378, Advance Auto Parts has exactly what you need with our selection of Carquest Premium Engine Cooling Parts. We have 3 Carquest Premium Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $86.99 and an average cost of $90.66, you’ll find the perfect Engine Cooling Part for your needs and budget. Carquest Premium Engine Cooling Parts for the 2000 Peterbilt 378 come highly rated, with over 3 customer reviews and an impressive average rating of 4.5 stars. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Carquest Engine Coolant HD Thermostat, 15006
from $86.99
(1)
Carquest Engine Coolant HD Thermostat, 15006
“Would have been nice to know that you must order a new exhaust tube because the dimensions are not the same.. but other than that its fine. Also gaske”
Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15008
from $96.99
(1)
Carquest Heavy Duty Thermostat: With Seal, 180 Degrees, 15008
“Camshaft sensor worked good. Fit my 2006 Grand Prix 3.8L.”
Carquest Engine Coolant HD Thermostat, 15009
from $87.99
(1)
Carquest Engine Coolant HD Thermostat, 15009
“Good product”

FAQs for 2000 Peterbilt 378 Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2000 Peterbilt 378s?

Out of 31 Engine Cooling Parts that fit 2000 Peterbilt 378s, the following parts are the top sellers:

What’s the price range for 2000 Peterbilt 378 Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2000 Peterbilt 378 range from $4.99 up to $1,209.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2000 Peterbilt 378?

The average price for Engine Cooling Parts for the 2000 Peterbilt 378 is $128.61. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Peterbilt 378 model years?

Yes, we carry Engine Cooling Parts for 18 model years of Peterbilt 378s between 1988 and 2007. The following model years are the most popular for Engine Cooling Part purchases: 2007, 2006, 2005, 2004, 2003, 2002, 2001, 1999, and 1998.

What are the cheapest Engine Cooling Parts for my 2000 Peterbilt 378?

The cheapest 2000 Peterbilt 378 Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2000 Peterbilt models?

Yes. We stock Engine Cooling Parts for 8 other popular 2000 Peterbilt models. Some of the most popular are 2000 387 Engine Cooling Parts, 2000 379 Engine Cooling Parts, 2000 377 Engine Cooling Parts, 2000 330 Engine Cooling Parts, and 2000 357 Engine Cooling Parts.

What are the top-rated Engine Cooling Parts that fit the 2000 Peterbilt 378?

The one 2000 Peterbilt 378 Engine Cooling Part we have in stock is the Carquest Coolant Temperature Sensor, WTA2372. It costs $4.99.

What types of Engine Cooling Parts do you sell for my 2000 Peterbilt 378?

As of 8/2/26, these are some of the most in-demand types of Engine Cooling Parts for a 2000 Peterbilt 378:

Can I get help with 2000 Peterbilt 378 Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Peterbilt Engine Cooling Parts and more.

What is your return policy for Peterbilt 378 Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Peterbilt 378 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.